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NPHC San Diego Group

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The Global Analgesics Market: Navigating the Opioid Crisis, Advancements in Non-Opioid Pain Management, and the Rise of Chronic Pain Prevalence


The global analgesics market is undergoing a transformative period, fundamentally reshaping in response to the pervasive opioid crisis and the escalating demand for safer, non-addictive pain relief options, making this a critical topic for group discussion. The paradigm shift is visible in the intense focus on developing and commercializing non-steroidal anti-inflammatory drugs (NSAIDs) with improved safety profiles, new modalities of nerve blocks, and various non-opioid pharmaceutical agents targeting novel pain pathways, such as inhibitors of the Nav1.7 sodium channel. The inherent risks associated with opioid analgesics, including dependence, addiction, and respiratory depression, have led regulatory bodies worldwide to enforce stricter prescribing guidelines, consequently dampening the growth of this segment but simultaneously spurring innovation in alternatives. Discussing the societal and economic burden of chronic pain, which affects a substantial percentage of…

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